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2024

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07

Clinical trial sample testing


Clinical trial sample testing

Development and validation of a one-stop AAV gene therapy analysis methodology, preparation of clinical sample collection kits and writing of laboratory manuals, as well as biological sample analysis

Genetic level testing

Biological distribution and virus shedding (PCR/ddPCR, detecting AAV copy numbers in serum, tears, and other matrices)

NGS second-generation sequencing (ophthalmic panel/WES)

Immunoassay detection

Anti AAV ADA (ELISA, detecting anti AAV binding antibodies in human serum samples)

Anti AAV Nab (Cell based NAb, a neutralizing antibody against AAV detected on a cellular platform in human serum samples)

ELISPOT (detection of specific T cells secreting IFN - γ)

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